Niki Chondrogianni received her BSc and PhD in Biological Sciences from the Department of Biology, University of Athens and post-doctoral training at the National Hellenic Research Foundation (NHRF) in Greece. She has also worked as a training/visiting fellow in the Foundation of Research and Technology-Hellas, Institute of Molecular Biology and Biotechnology with Prof. Tavernarakis, in the University Denis Diderot-Paris, Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement with Prof. Friguet and in the University of Bristol, Laboratory of Biochemistry (Proteasomes and intracellular proteolysis) with Prof. Rivett. She was elected Research Assistant Professor in 2009 and promoted to Research Associate Professor in 2013 at the NHRF. She is an author and co-author of several research articles in eminent journals with over 970 citations and she has contributed 4 chapters in international books. She is a patent holder that has resulted in the development of novel anti-aging products. She has received several awards including the Catherine Pasquier Award. She has teaching experience in courses at the University of Athens (Department of Biology and Medical School).
Her scientific activities focus in the identification of factors and pathways that regulate human aging with particular interest on the regulation of the proteasome and protein degradation during aging, senescence and response to oxidative stress. She is also focusing on the role of the transcription factor Nrf2 during the aging and senescence progression with emphasis on the Nrf2-mediated proteasome regulation. She has been active on identifying natural and chemical compounds with antioxidant properties that can serve as Nrf2/proteasome activators thus leading to cellular or organismal longevity. Since 2009, she has also included the C. elegans model organism in her model systems, seeking for the role of proteasome in the lifespan of this organism and the involved genetic pathways.