Tilman Grune is the Scientific Director of the German Institute of Human Nutrition and Full Professor of Molecular Toxicology at the University of Potsdam.
Studies of Medical Biochemistry in Moscow, Russia, Graduation at the Humboldt University Berlin (Charité), Germany, followed by post-doc positions in Berlin, Germany, and Albany (NY), US, several faculty positions in Berlin, Germany, and Düsseldorf, Germany, and full professorship at the University of Hohenheim, Stuttgart, Germany and at the Friedrich-Schiller-University Jena, Germany.
Editor-in-Chief of Redox Biology and member of the editorial board of several journals, including Free Radic. Biol. Med., Mol Asp. Med., Arch. Biochem. Biophys..
Chairman of the European COST network CM1001 on 'Nonenzymatic posttranslational protein modification' and vice-chair of the European project MARK-AGE on 'Biomarkers of Aging' Publications >350, h-Index 49.
The research is focused on the oxidative stress response of cells. The oxidative damage to proteins, the protection of proteins from oxidation and the fate of a protein if it is oxidized as well as biomarkers of nutrition and oxidative stress are major research topics.
Recently we focus on oxidation-related changes in the aging process. Model systems of aging are employed to investigate processes of lipid peroxidation, protein oxidation, the removal of oxidized protein and effects of nutritional components on these processes. A central role in these investigations is the investigation of functional consequences of the formed age-related protein aggregates.